2 or more items
receive a 5% discount !

Purchase 2 or more items
and receive a 5%
discount !

Oriveda's focus is on selling well-researched medicinal mushroom extracts of superior quality. The composition of the extracts and the dosage recommendations are in line with the existing research, not 'made up'.

Our business is based on common sense and pragmatism. We feel that every claim of quality should be backed up with facts.

Every batch of our products is tested for both safety (heavy metals) and active ingredients. We use objective ISO 17025 certified laboratories.

You don't have to take our word for it when we claim premium quality - you can verify it. We introduced the concept of objective lab testing in 2010. We are still one of the very few vendors that share actual lab test reports with our customers. No deceiving home-made 'certificates of analysis', no conflicts of interest ('in-house testing' haha).

For some bullet-points just click here.

• Therapeutically speaking, ORIVeDA extracts are the most powerful extracts available worldwide, with guaranteed levels of the most important bioactive components and the highest bioavailability possible. And this is not just a marketing statement.

• Our authorized supplement facts labels and Google make it easy to compare our products with others. As said, our Certificates of Analysis from independent third party laboratories are available here.

• Since we started as a business we have always emphasized the use of extracts, being the only reliable way to accomplish therapeutic effects.

• Already in 2012 we started specifying beta-glucans (the main active ingredient of most medicinal mushrooms) on our supplement fact labels. This was a time when 95 % of mushroom supplements had zero specifications (not being extracted) and the rest mentioned 'polysaccharides' at best, a broad term covering a lot of non-bioactive compounds, in the core unsuitable as a quality marker. Currently beta-glucans are widely accepted as a quality marker, using an AOAC-validated test method.

• We are the first ones specifiying cordycepin as a quality marker for Cordyceps and the first and the only ones to specify the ganoderic acids that are the trademark of Reishi. In short, we have set and pointed out quality standards since we started.

Our approach makes it easy for consumers to choose the right product and they're less likely to be deceived by marketing tricks. Check our FAQ for additional details.

• The value-for-money you get with our products is excellent. Not only are our prices often lower than others, but the level of bioavailable active ingredients in our extracts is usually much higher, in some instances over three times higher than the best of the rest. So, instead of spending $ 90 on “product X” you only have to spend $ 30 on our product for the same therapeutic potential.
And on top of that, as said before, we guarantee the bioavailability of the bioactives; your body can absorb and digest them 100%, so the therapeutic potential is maximal. And all these claims are supported by objective third party test results.

• In SE-Asia medicinal mushrooms have been used for many centuries. These countries therefore contain probably the best-informed and most critical consumers. We are proud to be able to claim that we are currently the only Western company selling mushroom extracts on a large scale to this region.
• A lot of the research on which our products' reputation is built is available and can be downloaded for free from the resources-section of our site.

• We ship directly (or indirectly - using local distributors) to almost all countries in the world, except warzones.

• We offer maximum personal service: we are online 7 days a week and your questions will be answered in great detail. Those questions are important: they help us develop new ideas and products. Keep them coming!

To contact us, please use the online form.

ORIVeDA is a registered brand name of ORIGO Holding BV, Amsterdam, The Netherlands. All rights reserved.

Make sure to check the FAQ before asking your questions !

  • 120 v-caps @ 450 mg 
  • (alcohol extract)

  • Contains sterols,
    erinacine A-R,
  • > 10 % Beta-Glucans
  • > 1.9 % Polyphenols

  • 180 v-caps @ 300 mg 
  • (1:1 lossless water extract)

  • Contains sterols,
    hericenone A-J,
    Hericene A-C,
    Erinacerin A+B
  • > 40 % Beta-glucans

Produced in compliance with the following quality standards :
  • ISO 9001
  • ISO 22000
  • cGMP
  • and also
  • Halal
  • Koosjer
  • USDA organic (EcoCert)
About Lion's Mane
L+ Combi Package
2 x 1 KG (bulk)
  • 120 v-caps @ 450 mg 
  • Alcohol Extract

  • Contains sterols,
    erinacine A-R,
  • > 10 % Beta-Glucans
  • > 1.9 % Polyphenols

  • 180 v-caps @ 300 mg 
  • 1:1 Water Extract

  • Contains sterols,
    hericenone A-J,
    Hericene A-C,
    Erinacerin A+B
  • > 40 % Beta-glucans

About Lion's Mane

Oriveda Lion's Mane is the only one in line with all research

Lion’s Mane contains over 70 bioactive ingredients and can be considered one of the most interesting mushrooms for gaining and maintaining good health. Very few mushrooms cover such a wide spectrum of therapeutic potential.

Science has been researching Lion's Mane mushrooms for several decades now, but barely scratched the surface so far. Below we've listed the main targets in research*.
Take notice: this list should not be interpreted as a list of medical claims ! For an extensive background click here ( page opens in new window ).

• Its potential for Immunomodulation

A shared property of all mushrooms is said to be immune-modulation. Key ingredients are mainly beta-glucans. Water extracted Lion’s Mane can have high levels of beta-glucan. Check the supplement label !

Considering that our immune system is the core of our health this is a very important property - allergies, inflammations, infections, auto-immune diseases and many old-age health issues are all immune-related. Also see our dedicated article about the immune system

• Its potential for Anti-Gastritis and Anti-Ulcer effects

Traditionally hot water-extracted Lion's Mane was used to treat peptic ulcers and chronic gastritis. Beta-glucans are the main bioactive compounds.

• Its potential for balancing good and bad cholesterol

Beta-glucans support a healthy balance between good and bad cholesterol. In the EU this health claim has been ratified by the EFSA.

A healthy balance between LDL (bad) and HDL (good) cholesterol helps with preventing high blood pressure and supports a healthy cardio-vascular system: less plaque, stronger arteries. 

Lion’s Mane also contains trace amounts of Lovastatin.

• Its potential for Anti-Diabetic effects

Like all mushrooms high in beta-glucans, Lion's Mane supports maintaining healthy blood sugar levels. High blood sugar levels are very damaging in the long run. Nerve damage / diabetic neuropathy is a major side effect of long-term high blood sugar levels.

In recent years a lot of research has been conducted into Lion’s Mane’s potential to help repair damaged nerves. Beta-glucan (normalising blood sugar levels) and terpenes (NGF-induction / nerve-repair) are the key ingredients here and are both present in good quality Lion's Mane. Check the supplement facts label !

• Improving cognitive functions and stimulating the Nerve Growth Factor

Nerve growth factor (NGF) is a secreted protein that is important for the growth, maintenance, survival and regeneration of nerve cells, and is considered critical for their survival. Without it, these nerve cells / neurons will die, causing both cognitive and motoric problems. The discovery of the NGF was in the 1950s, and the scientists responsible received the Nobel Prize in 1986 for this, when the importance of the NGF was finally acknowledged.

NGF prevents or reduces the degeneration of nerve cells such as caused by neurodegenerative diseases (e.g. Alzheimer's) and aging. A positive effect on myelination was also found.

Lion's Mane contains several compounds that appear to stimulate NGF production. NGF is stimulating nerves that are damaged due to e.g. accidents or declining due to aging to regrow to a certain extent*. Its main effect however appears to be slowing down the decline of the nerve system due to age. The main compounds responsible are alcohol-soluble terpenoids, and these are classified in two groups:

Hericenones (found in the fruiting body)
Erinacines (found in the mycelium)

Apart from those two groups research suggests there might be other yet-to-be-discovered compounds or synergetic combinations of compounds in Lion's Mane with similar potential.

These are so far the only active substances found in natural products that can induce the production of the NGF and the related BDNF (Brain-Derived Neurotropic Factor). These bioactives therefore might have great potential for -indirectly- repairing neurological damage, improving cognition and reflexes and, even more significant, to help slowing down the development of neurodegenerative diseases such as Alzheimer's.

We quote from a recent case study (duration: 16 weeks) performed with 50- to 80-year-old Japanese men and women diagnosed with mild cognitive impairment: [...] At weeks 8, 12 and 16 of the trial, the [Lion's Mane] group showed significantly increased scores on the cognitive function scale compared with the placebo group. The [Lion's Mane] group's scores increased with the duration of intake.[...] The results obtained in this study suggest that [Lion's Mane] is effective in improving mild cognitive impairment."

The full article can be read here.

• Its potential effects on menopausal problems, depression, anxiety

The NGF / BDNF-inducing bioactives in Lion's Mane also appear to have an effect on other areas of the brain, including areas that are related to Rett syndrome and bipolar disorder. Like, the menopause and obesity also include a mental element. Stress and/or anxiety are usually a precipitating factor in these and might negatively affect the levels of NGF.

We quote from a recent case study (2010; duration: 4 weeks) performed with 30 women in the menopausal age: [...] "Concentration", "irritating" and "anxious" tended to be lower than the placebo group. Our results show that HE intake has the possibility to reduce depression and anxiety and these results suggest a different mechanism from NGF-enhancing action of H. erinaceus.[...]".

The full article can be read here

• Side effects and safety

There are no known noteworthy side effects. Some very sensitive people might experience mild side effects due to their genetic wiring.

Mushroom extracts with a high level of beta-glucans should never be used together with immune-suppressants, like those prescribed after a transplant. 

The blood sugar lowering effects can cause fatigue in those that are highly susceptible. In general these people are also very susceptible to e.g. caffeine and alcohol, or are diabetic. Taking the extract together with a sugar-containing liquid can neutralise this effect. Diabetics might have to adjust their medication; we recommend to discuss this with a medical professional.

Hericium erinaceus, Lion's Mane, BDNF, NGF (Nerve Growth Factor), erinacine, hericenone

* The statements on this page have not been evaluated by the FDA or the EFSA.
This product is not intended to treat, cure or prevent any disease.
Do not use this product instead of regular medication.

Oriveda's L+ combination

Oriveda Lion's Mane L+ is the only one in line with all research

Oriveda's L+ has been upgraded in May 2020. It is currently a combination of two separate supplements that reinforce and complement each other, and which can be mixed, dosed and balanced against each other according to your own liking.

  • The L+ combi includes:
  • a full spectrum, lossless 1:1 hot water fruiting body extract, 180 capsules @ 300 mg
  • a pharma-grade pure mycelium alcohol extract, 120 capsules @ 450 mg.
  • This combi can cover 2 - 4 months (depending on personal dosing preferences)

This supplement combination covers the full spectrum of Lion's Mane 's therapeutic potential.

It is the only LM product that is truly 100% in line with all existing research: clinical, in vivo and in vitro. The key bioactives are all specified and quantified and their presence, percentage and bioavailability is guaranteed.

Click here to see the authorized 'Supplement Facts' labels with all relevant specifications.

more details...

Oriveda's lossless 1:1 hot water extract contains the full Lion's Mane fruiting body in a bioavailable form. Nothing was filtered out, both soluble and insoluble bioactives are still present in their natural synergy. In this case 'lossless' is crucial because we want the product to be 100% in line with the existing clinical research.

Three out of the five existing human case studies were done with non-extracted dried Lion's Mane fruiting body powder; by extracting this dried powder (like we did) the bioavailability / therapeutic effect increases ± 4 - 10 times according to research, and the required dosage drops from ± 2 - 3 grams daily to ± 600 - 900 mg daily.

Concentrated water extracts are not in line with LM research because all non-soluble matter was filtered out, including the NGF-inducing terpenes, sterols and other interesting bioactive compounds.

The clinical studies noticed significant effects on cognition, moderate depression and anxiety. Usually hericenones are pointed out as being responsible for the NGF-inducing effects of the fruiting body. However, there is also research explicitly stating that hericenones have zero effect on cognition / NGF-induction.

So it is possible there might be other yet unknown bioactive compounds or synergetic combinations of compounds responsible for the observed effects. It therefore makes sense to use an unfiltered 1:1 full-spectrum extract in this case; all fruiting body compounds are present in a bioavailable form.

Another fact overlooked by other vendors: Lion's Mane contains mainly insoluble bioactive beta-glucan. By concentrating an extract (8:1, 20:1) the insoluble matter is filtered out. In the case of Lion's Mane that will result in an extract with significantly less beta-glucan and therapeutic potential. Our lab tests proved this as well, so all the more reason to use the 1:1 lossless version.

Oriveda 's pharmaceutical grade mycelium extract is the worlds first and only alcohol extract based on pure liquid-grown mycelium. The emphasis is on the alcohol-soluble terpenes / terpenoids; i.p. a group of diterpenes known as erinacines. The two most recent clinical trials (2019/2020) were using pure mycelium.

Erinacines are seen as the most powerful NGF-inducers in Lion's Mane. They are only found in the mycelium. We have used a custom composition (a nutrients formula) for the liquid substrate in which the mycelium is growing; its purpose is to increase the production of erinacines, i.p. erinacine A. See our supplement facts label for the results.

hide details...

* The statements on this page have not been evaluated by the FDA or the EFSA.
This product is not intended to treat, cure or prevent any disease.
Do not use this product instead of regular medication.
Difference in effects between extracts and powdered mushrooms

Immunological effects of 39 mushroom supplements compared. [source]

supplement facts label Oriveda LION'S MANE (L+)