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The main bioactive compounds found in all mushroom extracts are beta-glucans (to be more specific: (1>3)(1>6) ß-D-glucans - a type of bioactive polysaccharides).
Beta-glucans give mushroom extracts their immune-modulating properties and contribute to the cholesterol-normalizing effects mushroom extracts are known for.
Three different types of very pure mushroom beta-glucan have been combined in ORIVeDA CCCE®. This increases the therapeutic bandwidth; it helps to create additional synergy and it improves the immune-modulating potential. The mushrooms included in this mix are Lion's Mane, Cordyceps, Maitake and Turkey Tail.
Beta-glucans are, simply put, long chains of molecules composed of a backbone with side-branches appearing at regular intervals, like ribs from a spine. They are very large macromolecules. The amount of branching, the intervals at which these branches appear and the molecular weight and solubility of beta-glucans are responsible for a wide array of physiological effects in both humans and animals. Our research section has a lot of background on this if you want more details.
Mushroom beta-glucan is much more bioactive than the beta-glucan found in other sources such as oats, barley and yeast. See our dedicated article for all details.
Already mentioned were (1>3)(1>6) ß-D-glucans (the numbers refer to the branching and the intervals at which these branches appear). Some mushrooms also contain (1>4)(1>6) ß-D-glucans (like the Coriolus versicolor -aka Turkey Tail-) and (1>6)(1>3) ß-D-glucans, which are only found in Maitake (Grifola frondosa).
All of these can trigger unique effects in the human immune system. In ORIVeDA CCCE® these three types have been combined into a unique synergistic formula.
Proteo-glycans (found in Coriolus versicolor -PSP-, and Maitake) are also important bioactives. These contribute to the synergy.
Cordyceps militaris contributes a significant level of cordycepin and adenosine to this blend. (As a matter of fact the specifations of CCCE as a whole are better than regular stand-alone Cordyceps extracts!) Cordycepin and adenosine are both nucleosides that show a variety of health effects.
Cordycepin (3'-deoxyadenosine) is seen as a revitaliser and said to improve the libido of both men and women. It has a vasodilating effect and can increase the intake of oxygen in the lungs.
CCCE stands for 'Cessante Causa, Cessat Effectus' which is Latin for 'by removing the cause you remove the effect'. It's referring to the immunological effect: if your immunity is optimal you have less chance to get sick.
CCCE® is a powerful immune-supporting dietary supplement, designed to help counter the negative effects of age and chronic stress on our immune system. CCCE® also has revitalising properties and supports developing the proper balance between good and bad cholesterol.
CCCE® is a blend of Maitake, Lion's Mane, Turkey Tail and Cordyceps militaris; 25% of each. All four are exceptionally pure extracts with a high level of immune-modulating high-molecular weight beta-glucans and proteo-glycans.
On top of that this blend contains a high level of cordycepin; in fact much more than whatever Cordyceps-only extract guarantees (except, of course, Oriveda's C+, which has twice the amount of CCCE's cordycepin).
Beta-glucans help to gain and maintain an optimal quality of life and support a feeling of well-being and vitality.
Click here to see our authorized 'Supplement Facts' label.
Immunological effects of 39 mushroom supplements compared. [source]